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Each gram ointment contains Acyclovir BP 30 mg.
Acyclovir is an antiviral agent. It is highly active against Herpes simplex and Varicella zoster in vitro. It is dependent on conversion by viral thymidine kinase, to the active triphosphate compound which then appears selectively, inhibit Herpes virus DNA polymerase enzyme. Acyclovir Ointment rapidly absorbs through the corneal epithelium & superficial ocular tissue, with the result that viral toxic concentration are achieved in aqueous humour.
Indications And Uses
Clovir Eye Ointment is used for the treatment of Herpes simplex keratis.
Dosage And Administration
Apply ointment into lower conjunctival sac five times daily at 4 hours interval; continue for minimum 3 days after healing.
In some patient mild & transient stringing may occur after application. Also superficial punctuate keratopathy& Blepharitis have been reported.
Use In Pregnancy Lactation
No adverse report has been recorded during the use of Acyclovir Eye Ointment in pregnancy & lactation.
It is contraindicated to the patients with known history of hypersensitivity to Acyclovir.
Clovir Eye Ointment should not be used after one month from the date of opening the tube.
Clovir is available in 5 gm tube.