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Dexlan
Dexlansoprazole INN
| NAME | STRENGTH | PACK SIZE | DOSAGE FORM |
|---|---|---|---|
| Dexlan 30 | 30 mg | 10X10 | Capsule |
| Dexlan 60 | 60 mg | 3X10 | Capsule |
Description
Dexlansoprazole is a PPI that suppresses gastric acid secretion by specific inhibition of the (H+, K+)-ATPase in the gastric parietal cell, resulting in potent inhibition of gastric acid secretion with prolonged elevation of intragastric pH.
Composition
Dexlan-30: Each capsule contains Dexlansoprazole INN 30 mg as enteric coated pellets. Dexlan-60: Each capsule contains Dexlansoprazole INN 60 mg as enteric coated pellets.
Indications And Uses
Dexlan (Dexlansoprazole) is a proton pump inhibitor used to treat- 1. Healing of all grades of erosive esophagitis 2. Maintaining healing of erosive esophagitis 3. Heart burn associated with non-erosive Gastroesophageal reflux disease (GERD)
Dosage And Administration
Dexlan (Dexlansoprazole) is a proton pump inhibitor used to treat- 1. Healing of all grades of erosive esophagitis 2. Maintaining healing of erosive esophagitis 3. Heart burn associated with non-erosive Gastroesophageal reflux disease (GERD)
Side Effect
Side effects are rarely seen; such as diarrhea, abdominal pain, nausea, vomiting, flatulence etc
Precaution
Patients taking concomitant Warfarin may require monitoring for increases in international normalized ratio (INR) and prothrombin time. Increases in INR and prothrombin time may lead to abnormal bleeding and even death.
Use In Pregnancy Lactation
Dexlansoprazole is considered a pregnancy Category B medication. This means that dexlansoprazole is probably safe for use during pregnancy, although the full risks are currently unknown.
Drug Interactions
Dexlan (Dexlansoprazole) may interfere with the absorption of drugs for which gastric pH is important for bioavailability (e.g., Ampicillin esters, Digoxin, iron salts, Ketoconazole).
Overdosage
There have been no reports of significant overdose of Dexlansoprazole. It is not expected to be removed from the circulation by hemodialysis. If an overdose occurs, treatment should be symptomatic and supportive.
Storage
Store in a cool and dry place. Keep away from light and out of reach of children.
Contraindications
Dexlan (Dexlansoprazole) is contraindicated in patients with known hypersensitivity to any component of the formulation. Hypersensitivity and anaphylaxis have been reported with Dexlansoprazole
How Supplied
Dexlan-30: Each commercial box contains 10X10 capsules of Dexlansoprazole INN 30 mg as enteric coated pellets. Dexlan-60: Each commercial box contains 3X10 capsules of Dexlansoprazole INN 60 mg as enteric coated pellets.