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Travoprost USP

Avost 0.004% w/v 3 ml Eye drops


Each ml contains Travoprost USP 0.04 mg.

Travoprost is a synthetic prostaglandin analogue. It is a selective FP prostanoid receptor agonist which is believed to reduce intraocular pressure by increasing uveoscleral outflow.

Elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Use in adults: One drop in the affected eye once-daily in the evening. The dosage of Travoprost should not exceed once daily since it has been shown that more frequent administration may decrease the normal intraocular pressure.

Hypersensitivity to Travoprost or to any of the excipients.

The most common ocular adverse effect is ocular hyperemia. Ocular adverse events reported at an incidence of 5-10% included decreased visual acuity, eye discomfort, foreign body sensation, pain, and pruritus. Ocular adverse events reported at an incidence of 1-4% included, abnormal vision, blepharitis, blurred vision, cataract, conjunctivitis, dry eye, flare, iris discoloration, keratitis, lid margin crusting, photophobia, subconjunctival hemorrhage, and tearing.

Travoprost eye drops should be used with caution in patients with active intraocular inflammation & macular edema. In case of patients with mild to severe hepatic impairment and renal impairment (creatinine clearance as low as 14 ml/min) no dosage adjustment is necessary. Travoprost should not be administered while wearing contact lenses. Lenses may be reinserted 15 minutes following administration of Travoprost eye drop.

Pregnancy category C. It is unknown whether Travoprost from eye drops is excreted in human breast milk. Animal studies have shown excretion of Travoprost and metabolites in breast milk. The use of Travoprost by breast-feeding mothers is not recommended.

No specific interaction was observed with Travoprost eye drops.

Store in a cool, dry place and protected from light. Keep out of reach of children. Discard the container 4 weeks after opening.

Each plastic dropper bottle contains 3 ml Sterile Eye Drops.